REVIEW PAPER
Recent advance of in vitro models in natural phytochemicals absorption and metabolism
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Chao Zhao 1,2,3
 
 
 
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1
College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
 
2
Engineering Research Centre of Fujian-Taiwan Special Marine Food Processing and Nutrition, Ministry of Education, Fuzhou 350002, China
 
3
Key Laboratory of Marine Biotechnology of Fujian Province, Institute of Oceanology, Fujian Agriculture and Forestry University, Fuzhou 350002, China
 
 
Submission date: 2021-12-06
 
 
Final revision date: 2022-01-26
 
 
Acceptance date: 2022-02-25
 
 
Online publication date: 2022-03-23
 
 
Publication date: 2022-03-23
 
 
Corresponding author
Chao Zhao   

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
 
 
eFood 2021;2(6):307-318
 
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ABSTRACT
Natural phytochemicals absorption and metabolic process are mainly in the human gut. Simulating the absorption and metabolism of natural phytochemicals in vitro to predict the rate and degree of absorption of natural phytochemicals provides convenience for many researchers. However, in this process, many physiological factors in vitro are affected, such as stomach and intestinal juice composition, pH, intestinal transmission rate and so on. In recent years, the research methods have gradually improved to make these models more suitable for the natural phytochemicals absorption process, in vitro simulation models have become an essential means to study natural phytochemicals absorption. Therefore, this paper introduces the advantages and disadvantages of commonly used in vitro simulation models of natural phytochemicals absorption and metabolism, as well as briefly introduces the working principle of each model. To provide a theoretical basis for simulating natural phytochemicals absorption in vitro and development and utilization of natural phytochemicals.
eISSN:2666-3066
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